Orthosteric and allosteric modulation of human HCAR2 signaling complex 2024-04-01
Pan-Cancer Single-Nucleus Total RNA Sequencing Using snHH-Seq 2024-04-01
A second-generation M1-polarized CAR macrophage with antitumor efficacy 2024-04-01
Conserved Enzymatic Cascade for Bacterial Azoxy Biosynthesis 2024-04-01
GDF11 slows excitatory neuronal senescence and brain ageing by repressing p21 2024-04-01
Polyethylene glycol (PEG)-associated immune responses triggered by clinically relevant lipid nanoparticles in rats 2024-04-01
TRPM2 as a conserved gatekeeper determines the vulnerability of DA neurons by sensing ROS and calcium dyshomeostasis 2023-10-26
Metabolic Reprogramming via ACOD1 depletion enhances function of human induced pluripotent stem cell-derived CAR-macrophages in solid tumors 2023-10-26
Postsynaptic histamine H3 receptors in ventral basal forebrain cholinergic neurons modulate contextual fear memory 2023-10-26
Near-Infrared Photothermal Manipulates Cellular Excitability and Animal Behavior in Caenorhabditis elegans 2023-10-26
Hydroxytryptophan biosynthesis by a family of heme-dependent enzymes in bacteria 2023-10-26
TOR-mediated Ypt1 phosphorylation regulates autophagy initiation complex assembly 2023-10-26
Glutamine production by Glul promotes thermogenic adipocyte differentiation through Prdm9-mediated H3K4me3 and transcriptional reprogramming 2023-10-26
NRF2 has a splicing regulatory function involving the survival of motor neuron (SMN) in non-small cell lung cancer 2023-10-26
A GSTP1-mediated lactic acid signaling promotes tumorigenesis through the PPP oxidative branch 2023-10-26
VAPB-mediated ER-targeting stabilizes IRS-1 signalosomes to regulate insulin/IGF signaling 2023-10-26
ARIH1 activates STING-mediated T-cell activation and sensitizes tumors to immune checkpoint blockade 2023-10-26
The muscle-enriched myokine Musclin impairs beige fat thermogenesis and systemic energy homeostasis via Tfr1/PKA signaling in male mice 2023-10-26
Structural basis of ligand activation and inhibition in a mammalian TRPV4 ion channel 2023-10-26
An analytical framework for decoding cell type-specific genetic variation of gene regulation 2023-10-26